ITPA protein, an enzyme that eliminates deaminated purine nucleoside triphosphates in cells
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چکیده
منابع مشابه
ITPA protein, an enzyme that eliminates deaminated purine nucleoside triphosphates in cells.
Inosine triphosphate pyrophosphatase (ITPA protein) (EC 3.6.1.19) hydrolyzes deaminated purine nucleoside triphosphates, such as ITP and dITP, to their corresponding purine nucleoside monophosphate and pyrophosphate. In mammals, this enzyme is encoded by the Itpa gene. Using the Itpa gene-disrupted mouse as a model, we have elucidated the biological significance of the ITPA protein and its subs...
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ژورنال
عنوان ژورنال: Mutation Research/Genetic Toxicology and Environmental Mutagenesis
سال: 2010
ISSN: 1383-5718
DOI: 10.1016/j.mrgentox.2010.06.009